Xueji Zhang Selected Research

p38 Mitogen-Activated Protein Kinases

11/2016	Inhibition of Aurora kinases induces apoptosis and autophagy via AURKB/p70S6K/RPL15 axis in human leukemia cells.
1/2015	Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
1/2015	Induction of apoptosis and autophagy via sirtuin1- and PI3K/Akt/mTOR-mediated pathways by plumbagin in human prostate cancer cells.
1/2015	Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells.
1/2015	Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells.
1/2015	The pan-inhibitor of Aurora kinases danusertib induces apoptosis and autophagy and suppresses epithelial-to-mesenchymal transition in human breast cancer cells.
1/2015	The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells.
1/2015	Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells.

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Xueji Zhang Research Topics

Disease

66	Neoplasms (Cancer) 07/2022 - 01/2010
8	Hypoxia (Hypoxemia) 03/2022 - 02/2018
5	Prostatic Neoplasms (Prostate Cancer) 02/2022 - 01/2015
5	B-Cell Lymphoma (Lymphoma, B Cell) 01/2015 - 01/2015
4	Lung Neoplasms (Lung Cancer) 10/2022 - 01/2020
4	Infections 01/2022 - 01/2015
4	Alzheimer Disease (Alzheimer's Disease) 08/2021 - 09/2015
4	Breast Neoplasms (Breast Cancer) 10/2020 - 01/2015
4	Neoplasm Metastasis (Metastasis) 12/2019 - 08/2013
3	Melanoma (Melanoma, Malignant) 09/2020 - 01/2018
3	Pancreatic Neoplasms (Pancreatic Cancer) 11/2019 - 01/2015
3	Carcinogenesis 01/2019 - 11/2016
2	Stroke (Strokes) 12/2021 - 09/2004
2	Colorectal Neoplasms (Colorectal Cancer) 12/2021 - 01/2018
2	Wounds and Injuries (Trauma) 11/2020 - 01/2010
2	Disease Progression 01/2020 - 10/2015
2	Hyperthermia 12/2018 - 01/2010
2	Leukemia 11/2016 - 01/2015
2	Lymphoma (Lymphomas) 11/2016 - 01/2015
2	Type 2 Diabetes Mellitus (MODY) 12/2015 - 10/2015
2	Body Weight (Weight, Body) 10/2015 - 09/2014
2	Stomach Neoplasms (Stomach Cancer) 01/2015 - 01/2015
2	Hematologic Neoplasms (Hematological Malignancy) 01/2015 - 01/2015
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2015 - 01/2015
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2015 - 03/2014
1	Psoriasis (Pustulosis Palmaris et Plantaris) 12/2022
1	Urinary Bladder Neoplasms (Bladder Cancer) 07/2022
1	Polyps 05/2022
1	Glioma (Gliomas) 05/2022

Drug/Important Bio-Agent (IBA)

17	Biomarkers (Surrogate Marker)IBA 12/2022 - 01/2012
17	MicroRNAs (MicroRNA)IBA 12/2022 - 01/2013
13	Pharmaceutical PreparationsIBA 05/2022 - 01/2013
9	1-phenyl-3,3-dimethyltriazene (PDT)IBA 03/2022 - 11/2017
8	Proteins (Proteins, Gene)FDA Link 12/2021 - 04/2014
8	Biological ProductsIBA 08/2021 - 01/2010
8	p38 Mitogen-Activated Protein KinasesIBA 11/2016 - 01/2015
7	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2022 - 01/2013
6	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2020 - 01/2013
6	Aurora Kinase AIBA 11/2016 - 01/2015
6	plumbaginIBA 01/2015 - 03/2014
5	CopperIBA 09/2021 - 01/2018
5	Glutathione (Reduced Glutathione)IBA 01/2021 - 01/2013
5	DNA (Deoxyribonucleic Acid)IBA 02/2020 - 03/2019
5	Therapeutic UsesIBA 01/2020 - 01/2015
5	Small Interfering RNA (siRNA)IBA 10/2018 - 01/2013
5	MLN 8237IBA 01/2015 - 01/2015
4	Metal-Organic FrameworksIBA 07/2022 - 01/2020
4	cupric sulfide (CuS)IBA 01/2022 - 01/2018
4	Antineoplastic Agents (Antineoplastics)IBA 05/2015 - 08/2013
3	SolutionsIBA 12/2022 - 12/2018
3	Photosensitizing Agents (Photosensitizers)IBA 03/2022 - 02/2018
3	Silicon Dioxide (Silica)FDA LinkGeneric 10/2020 - 12/2018
3	AcidsIBA 01/2017 - 01/2015
3	danusertibIBA 11/2016 - 01/2015
3	Aurora KinasesIBA 11/2016 - 01/2015
3	TOR Serine-Threonine KinasesIBA 01/2015 - 01/2015
3	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 01/2015 - 01/2015
2	Nucleic AcidsIBA 10/2022 - 01/2022
2	Adenosine Triphosphate (ATP)IBA 05/2022 - 01/2021
2	VanadiumIBA 03/2022 - 01/2019
2	Oxygen (Dioxygen)IBA 03/2022 - 11/2020
2	Tumor Biomarkers (Tumor Markers)IBA 01/2022 - 01/2020
2	AntioxidantsIBA 11/2021 - 01/2019
2	Amyloid (Amyloid Fibrils)IBA 08/2021 - 01/2018
2	Membrane Proteins (Integral Membrane Proteins)IBA 10/2020 - 01/2019
2	GraphiteIBA 01/2020 - 11/2017
2	CytokinesIBA 01/2020 - 01/2015
2	RNA (Ribonucleic Acid)IBA 01/2020 - 01/2018
2	Prostate-Specific Antigen (Semenogelase)IBA 01/2020 - 01/2018
2	Singlet OxygenIBA 01/2019 - 11/2017
2	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 01/2019 - 12/2018
2	Liposomes (Liposome)IBA 12/2018 - 01/2015
2	PolymersIBA 12/2018 - 01/2010
2	CateninsIBA 01/2018 - 01/2015
2	PolyethyleneimineIBA 02/2017 - 01/2013
2	Dipeptidyl-Peptidase IV InhibitorsIBA 12/2015 - 10/2015
2	SodiumIBA 05/2015 - 01/2013
2	CaspasesIBA 01/2015 - 01/2015
2	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2015 - 01/2015
2	NaphthoquinonesIBA 01/2015 - 01/2015
2	Amino Acids FDA Link 01/2015 - 01/2015
2	SirtuinsIBA 01/2015 - 01/2015
2	IsotopesIBA 01/2015 - 01/2015
2	Beclin-1IBA 01/2015 - 01/2015
2	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2015 - 01/2015
2	bcl-2-Associated X Protein (bcl 2 Associated X Protein)IBA 01/2015 - 01/2015
2	bcr-abl Fusion ProteinsIBA 01/2015 - 01/2015
1	HydrogelsIBA 12/2022
1	Hemoglobins (Hemoglobin)IBA 10/2022
1	aspartic acid glycine arginineIBA 07/2022
1	PolyphosphatesIBA 05/2022
1	ChlorophyllIBA 03/2022

Therapy/Procedure

26	Therapeutics 07/2022 - 01/2013
10	Drug Therapy (Chemotherapy) 11/2021 - 01/2013
6	Photochemotherapy (Photodynamic Therapy) 03/2022 - 11/2017
6	Photothermal Therapy 01/2022 - 11/2017
4	Precision Medicine 11/2020 - 11/2017
4	Lasers (Laser) 07/2019 - 01/2012
2	Bandages (Bandage) 11/2020 - 01/2010
2	Quantum Dots (Quantum Dot) 01/2019 - 11/2017